I kind of like Amy Farah Fowler. I recognize her, and not in a "Girl Sheldon" sort of way. I've worked with a few of her type in medicine-- usually someone anxious to go into research just as soon as they finish up that pesky residency.

Granted I loved "Blossom" (even though I was already an adult when it aired and really was too old for it) and so I'm probably predisposed to like the actress.

ITA on Sheldon/Penny. That one makes no sense to me at all, and it's everywhere. I kind of like that they can be friends without it being sexual. I have guy friends with no sexual component, and you don't see that much on TV.